Experimental periodontitis induced hypoadiponectinemia by IRE1α-mediated endoplasmic reticulum stress in adipocytes

Expiry Date
: 19/01/2030
CPD Units
: 3.00 Points

The article investigates how periodontitis-induced endoplasmic reticulum stress (ERS) affects hypoadiponectinemia in visceral adipocytes, revealing increased ERS protein expression and decreased adiponectin levels, with IRE1α as a key regulatory factor.

Keywords: Periodontitis, endoplasmic reticulum stress, hypoadiponectinemia, GRP78, IRE1a

Reading material:

Educational Objectives

Educational Aim:
To enhance understanding of the relationship between periodontitis and hypoadiponectinemia, particularly how periodontitis-induced endoplasmic reticulum stress (ERS) in visceral adipocytes affects adiponectin levels. It seeks to inform researchers and healthcare professionals about the underlying mechanisms of insulin resistance related to oral health, promoting further investigation and awareness of periodontal disease's systemic impacts.

Educational Outcomes:
Upon completion of this module practitioners should have a clear understanding of:

  1. The mechanisms of Insulin Resistance
  2. The role of IRE1α in Adiponectin Regulation
  3. The awareness of Periodontal Disease Impacts

Instructions for this Module

  • Read the supplied reading material and complete the quiz that follows;
  • You have three attempts to pass the quiz;
  • The pass grade is 70%;
  • You need to pass the quiz to claim your CPD certificate;
  • Please click on the CPD certificate link below to claim your CPD certificate and to update your CPD Manager.

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