Exploring the link between environmental chemical exposures and epigenetic modifications in diabetes mellitus

Expiry Date
: 13/03/2031
CPD Units
: 3.00 Points

The article reviews how environmental pollutants influence diabetes development via epigenetic modifications, including DNA methylation, histone changes, and miRNA regulation, affecting insulin resistance and glucose homeostasis.

Keywords: Diabetes mellitus, environmental pollutants, epigenetics, DNA methylation, histone modification, microRNA, AhR/CYP1 pathway, insulin resistance, glucose homeostasis, particulate matter, heavy metals, organic pollutants

Reading material:

Educational Objectives

Educational Aim:

To explore the impact of environmental chemical exposures on epigenetic modifications and their role in the development and progression of diabetes mellitus.

Educational Outcomes:
Upon completion of this module practitioners should have a clear understanding of:

  1. How environmental pollutants, including particulate matter, heavy metals, and organic chemicals, contribute to diabetes development.
  2. The mechanisms by which epigenetic modifications such as DNA methylation, histone modifications, and miRNA regulation affect glucose metabolism and insulin resistance.
  3. The role of the AhR/CYP1 pathway in mediating pollutant-induced metabolic dysfunction and its interplay with epigenetic changes.

Instructions for this Module

  • Read the supplied reading material and complete the quiz that follows;
  • You have three attempts to pass the quiz;
  • The pass grade is 70%;
  • You need to pass the quiz to claim your CPD certificate;
  • Please click on the CPD certificate link below to claim your CPD certificate and to update your CPD Manager.

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