Efficacy of aerobic exercise for HIV-associated neurocognitive disorders receiving ART: An RCT

This RCT shows 12-week aerobic exercise significantly improves activity and participation levels (small effect) in people with HIV-associated neurocognitive disorders on ART, though gains fade by 3 months.

Educational Objectives

Educational Aim:

This article aims to explain the efficacy of a 12-week moderate-intensity aerobic exercise programme in improving activity and participation levels (social wellbeing, emotional wellbeing, and overall function) in people living with HIV-associated neurocognitive disorder on antiretroviral therapy, and discuss its clinical implications and limitations.

Educational Outcomes:
Upon completion of this module practitioners should have a clear understanding of:

1. The significant improvements in social wellbeing, emotional wellbeing and overall activity/participation levels immediately after 12 weeks of moderate-intensity aerobic exercise in people with HAND on ART.
2. The small-to-moderate effect sizes (Cohen’s d = 0.55–0.90) and their clinical relevance for managing participation restrictions.
3. Why the benefits were not sustained at 3-month follow-up and outline practical recommendations for ongoing aerobic exercise in this population.

Instructions for this Module

• Read the supplied reading material and complete the quiz that follows;
• You have three attempts to pass the quiz;
• The pass grade is 70%;
• You need to pass the quiz to claim your CPD certificate;
• Please click on the CPD certificate link below to claim your CPD certificate and to update your CPD Manager.

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