Developments in Therapeutics Research for Ebola Virus Disease

Expiry Date
: 01/06/2025
CPD Units
: 3.00 Points
Rating
: Not yet rated.

Ebola virus is a contagious, lethal virus causing haemorrhagic fever and recent outbreaks warrant ongoing research into effective treatment strategies.

Keywords: Ebola virus, treatment, therapeutics

Reading material:

Educational Objectives

Educational Aim:

The aim of this article is to provide information about ongoing efforts needed to develop more effective strategies to treat Ebola outbreaks, particularly for individuals with severe disease, and for prevention and treatment of viral persistence.

Editor's comments:

The World Health Organization (WHO) confirmed that twenty-nine people, including four health workers, have died since the Ebola outbreak was declared in Uganda on 20 September 2022. The lack of a vaccine to treat the strain of Ebola responsible for the outbreak – the Sudan virus – is a concern.

Vaccines used to successfully curb recent Ebola outbreaks in the Democratic Republic of the Congo (DRC) are not effective against the Sudan virus. The WHO said several vaccines were in various stages of development, and these could begin clinical trials in Uganda in the coming weeks. 

The Africa Centres for Disease Control and Prevention, part of the African Union, said Uganda would host a ministerial meeting with neighbouring states and other African countries that had experienced Ebola outbreaks to explore ways of managing them.

Educational Outcomes:
Upon completion of this module practitioners should have a clear understanding of:

  1. Upon completion of this module practitioners should have a better understanding of the Pamoja Tulinde Maisha (PALM) study, which was a randomised, controlled trial of three investigational agents compared with a control group for the treatment of patients with Ebola virus disease, as well as the additional work needed to optimise Ebola virus disease treatment regimens for existing and future threats.

Instructions for this Module

  • Read the supplied reading material and complete the quiz that follows;
  • You have three attempts to pass the quiz;
  • The pass grade is 70%;
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